Professor & Chair
Medical Microbiology & Immunology
School of Medicine
Dr. Dandekar's research program is focused on the molecular pathogenesis of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections with special emphasis on gastrointestinal mucosal lymphoid tissue (GALT) as a major target organ of the viral infection and as a viral reservoir.
Current studies have been focused on determining the molecular mechanisms of the disruption of gut mucosal immune system in HIV infection and restoration during anti-retroviral therapy. Her research has utilized the SIV infected rhesus macaque model to investigate the pathologic effects of viral infection on the gut mucosal immune system and function.