Research Interests

Dr. Medici’s research interests include the effects of copper accumulation in the liver, as occurs in Wilson disease, on hepatic methionine metabolism, the regulation of gene expression by methylation, and consequent interactions with pathways of liver injury in particular lipogenesis and steatosis. She uses similar methods to study the effects of alcohol drinking on methionine metabolism and the development of alcoholic liver disease. Her studies use genetically altered mouse models of Wilson disease and alcoholic liver disease.